The Oviduct plays a very important role in modern poultry production systems as the number of eggs laid by breeder flocks and egg-producing hens reflects the commercial viability of poultry operations. It is also important to consider that the quality of eggs produced in the oviduct is a key factor in determining the success of poultry farms. Any disease of poultry can adversely affect egg production and quality either directly, by having effects on the reproductivity system, or indirectly, by affecting the health of the bird. Respiratory infections which result in air sacculitis may, in turn, infect the ovary and oviduct. In addition, some diseases infect the oviduct and ovary by ascending infection.

Chronic respiratory disease and synovitis in laying hens. Both infections are causing loss of productivity up to 20-25%. It is frequently difficult to diagnose the cause or causes of reduced egg quality because it is often a combination of factors that leads to poor egg quality. Management, nutrition, and disease may, in combination, result in a reduction in egg internal quality and/or eggshell quality. The most recent comprehensive review of diseases affecting egg quality is that of Spackman (1987). As the oviduct being a long tube containing multiple glands and blood vessels, it is involved in the production of albumen and shell membrane. The oviduct remains dormant at young age, subsequently it starts maturing and prime the ovary to produce various hormones involved in egg production. The complex intensive modern- day productions often lead to compromised growth of the oviduct. Nutritional factors, concurrent viral and bacterial infections and of course the Mycoplasma factor led to such conditions. It is often said that the Mycoplasma is a permanent enemy to the laying chickens leading to a huge economic loss.

Mycoplasma gallisepticum causes chronic respiratory disease (CRD) in chickens and often co-occurs with a respiratory virus infection (Ley, 2008). Oviduct infection can occur owing proximity to infected air sacs (Nunoya et al., 1997). M. gallisepticum (MG), involved in abnormal eggshells and production losses and what was caused by interactions with other infectious agents such as infectious bronchitis virus (Giambrone et al., 1977). MG causes production losses and, in the case of breeder flocks, decreased hatchability. The control of Mycoplasma in poultry often proves to be very challenging for poultry veterinarians. Worldwide, there are a few standard recommendations available. However, veterinarians have been able to develop successful strategies to manage Mycoplasma in poultry, often involving careful monitoring and implementation of preventative measures. It is possible to achieve good control by utilizing a synergistic combination of biosecurity measures, nutritional management, vaccination, essential oils, and anti-mycoplasma medications. By focusing on a comprehensive approach such as this, excellent outcomes can be achieved. There are two molecules offered by Immeureka, Tiamulin and Tylvalosin. We follow the classical practice of using such drugs therapeutically or as a preventive regime or as part of a weekly program determined by a poultry veterinarian. To ensure the best possible outcome, it is essential to use these molecules under the guidance of a poultry veterinarian.

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